Targeting Sphingoshine (SP) receptor for Multiple Sclerosis (MS) and P-glycoprotein to discover new anticancer agents for prostate cancer, Multi drug resistant (MDR) cancer
Development of new process for API/KSM and Flow Chemistry
Development of novel inhibitors of Sortase A for attenuating the virulence of Staphylococcus aureus”
Semi-synthesis of Indolizine, Pyrrolo Quinoline/Isoquinoline based natural product hybrids via 1,3-dipolar cycloaddition
N2 Fixation by Heterobimetallic Complexes under Visible Light for the Access of Organonitrogen Compounds as Potential Biological Targets
Live cell fluorescent labelling of Withaferin A targeted protein and their proteomics analysis
Oligonucletide, RNA, DNA and solid phase synthesis eureka
Natural products drug discovery (bioactive natural products)
Extraction, isolation, identification, structural modification (synthesis), bioactivity and mode of action of pharmaceutically important natural products
Bioassay guided approach
Metabolomics of medicinal plants
Development of bioassays for screening plant extracts and isolated compounds
Genome Analysis (transcriptome, proteome, metabolome)
Metabolite Profiling
Herb-Drug Pharmacokinetic interaction
Standardization of Phytopharmaceuticals using LC-MS, HPLC
Drug Metabolism of Phytopharmaceuticals
Development of animal models for human diseases such as Diabetes mellitus, Non alcoholic steatohepatitis, inflammatory bowel disease, neurological disorders
Scientific evidence for Indian traditional medicine systems such as Ayurveda, Homoeopathy, Siddha, etc.
Toxicity studies of phtochemicals and synthetic molecules using C. elegans as assay system and rodents
Exosomes as disease markers and drug delivery agents against various cancer models
Gene and protein expression studies
Diabetes and Diabetic complications
Chemotherapy induced Peripheral Neuropathy
Trauma induced Peripheral Neuropathy
Target identification
Virtual screening of natural compounds and chemical databases against important targets for hit identification
Ligand-based techniques
QSAR
3D-QSAR
Ligand based pharmacophore mapping
Structure-based techniques
Homology modelling
Docking
Target based pharmacophore mapping
Molecular dynamic simulation
ADME prediction
Electronic structure analysis
Quantum chemical studies of metabolic reaction pathways
Quantum chemical studies of organic reactions (Computation of transition state, energy of reaction, energy of activation)
Machine learning and deep learning approaches
Development of conventional dosage forms including parenteral, biologics for domestic market and later for regulated international markets.
Cater the analytical needs of small scale pharmaceutical industries through its well-developed analytical service facility.
Light activated dual drug delivery systems.
Novel formulations for delivering of drugs to back of the eye .
Microneedles for delivery of biomolecules .
Characterization of novel biomaterials from natural biowastes
Fabrication of customized implants
Hydrogel and medical textiles for wound healing and hemostasis
Surface modification, antimicrobial coating of medical devices
Bone, skin and cartilage tissue engineering
In vitro diagnostics (IVD) based on fluorescent probes and enzyme immobilization
Micro/nanodevices for drug delivery, cancer theranostics, live cell imaging
3D Bioprinting and Electrospinning
Piezoelectric nanomaterials for neo-tissue regeneration
Drug-Device combination products